Table 5.

Associations between regional MWF and either MetS risk score or adiposity sub-scores, controlling for age, age², sex, race, ethnicity, education, income, and regional ICVF.

DV	IV	Std. β	t	p	FDR-corrected p	ΔR2	Overall model fit
							Adjusted R2	p
UNC MWF	MetS	−0.47	−3.92	<0.001			0.17	0.003
	ICVF	0.27	2.18	.032			0.21	<0.001
	MetS	−0.45	−3.78	<0.001	<0.007	0.16 p<0.001
Prefrontal MWF	MetS	−0.37	−3.00	0.004			0.15	0.006
	ICVF	0.63	6.00	<0.001			0.41	<0.001
	MetS	−0.33	−3.24	0.002	0.005	0.07 p = 0.002
UNC MWF	Adiposity	−0.56	−5.19	<0.001			0.26	<0.001
	ICVF	0.22	1.85	0.069			0.28	<0.001
	Adiposity	−0.52	−4.89	<0.001	<0.007	0.20 p<0.001
Genu CC MWF	Adiposity	−0.40	−3.82	<0.001			0.31	<0.001
	ICVF	0.45	4.12	<0.001			0.42	<0.001
	Adiposity	−0.32	−3.32	0.001	0.004	0.07 p = 0.001
Prefrontal MWF	Adiposity	−0.46	−4.26	<0.001			0.23	<0.001
	ICVF	0.59	5.87	<0.001			0.46	<0.001
	Adiposity	−0.39	−4.28	<0.001	<0.007	0.11 p<0.001
mPFC MWF	Adiposity	−0.40	−3.68	<0.001			0.23	<0.001
	ICVF	0.23	1.99	0.050			0.26	<0.001
	Adiposity	−0.36	−3.29	0.001	0.004	0.09 p = 0.001
EC MWF	Adiposity	−0.36	−3.32	0.001			0.24	<0.001
	ICVF	0.41	3.94	<0.001			0.36	<0.001
	Adiposity	−0.29	−2.91	0.005	0.009	0.06 p = 0.005

Note: DV: dependent variable of a modal. IV: independent variables, in addition to age (centered), age², sex, race, ethnicity, education, income. For each DV (regional MWF), the first line (marked in grey) is presented for comparison and is a replication of the results presented in [26] (n = 90) with the current sample size (n = 89). The remaining two lines present the regression results for the two IVs of interest: regional ICVF and MetS/Adiposity. Std. β: standardized beta coefficient. ΔR²: R² change for MetS or adiposity scores in the final model.