1 |
The conclusion formulates recommendations for clinical practice not supported by the findings |
2/15 |
13.3% |
2 |
The title claims or suggests a beneficial effect of the experimental intervention not supported by the findings |
1/15 |
6.7% |
3 |
Selective reporting of or overemphasis on efficacy outcomes or analysis favoring the beneficial effect of the experimental intervention |
5/15 |
33.3% |
4 |
The conclusion claims safety based on nonstatistically significant results with a wide confidence interval |
2/15 |
13.3% |
5 |
The conclusion claims the beneficial effect of the experimental treatment despite a high risk of bias in primary studies |
5/15 |
33.3% |
6 |
Selective reporting of or overemphasis on harm outcomes or analysis favoring the safety of the experimental intervention |
0/15 |
0.0% |
7 |
The conclusion extrapolates the review findings to a different intervention (e.g., claiming efficacy of one specific intervention although the review covered a class of several interventions). |
0/15 |
0.0% |
8 |
Conclusion extrapolates the review's findings from a surrogate marker or a specific outcome to the global improvement of the disease |
1/15 |
6.7% |
9 |
Conclusion claims the beneficial effect of the experimental treatment despite reporting bias |
3/15 |
20.0% |
10 |
Authors hide or do not present any conflict of interest |
5/15 |
33.3% |
11 |
Conclusion focuses selectively on statistically significant efficacy outcome |
5/15 |
33.3% |
12 |
Conclusion claims equivalence or comparable effectiveness for nonstatistically significant results with a wide confidence interval |
3/15 |
20.0% |
13 |
Failure to specify the direction of the effect when it favors the control intervention |
6/15 |
40.0% |
14 |
Failure to report a wide confidence interval of estimates |
10/15 |
66.7% |
15 |
Conclusion extrapolates the review's findings to a different population or setting |
3/15 |
20.0% |