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. 2024 Jan 30;14:2501. doi: 10.1038/s41598-024-51839-5

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Experimental overview and lesion data. (A) Experimental timeline. (B) Schematic sagittal rat brain drawing depicting the tDCS area and the illumination area (photothrombotic stroke induction); midpoint of the areas in relation to bregma (dotted lines). (C) Representative image of a FJ-C-stained histological brain slice; stroke delineated in white; 1000-µm scale bar. Photothrombosis resulted in comparable (D) infarct volume and (E) extension of the caudal stroke border, independent of the group. 0.0 A/m² (n = 6), 0.8 A/m² (n = 5), 31.8 A/m² (n = 8), 47.8 A/m² (n = 7). mNSS modified neurological severity score, pasta pasta handling task, tDCS transcranial direct current stimulation. Data represent mean ± SEM, scatter = individual animals.