Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 30;14:2501. doi: 10.1038/s41598-024-51839-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effects of tDCS on neurological and behavioral deficits after photothrombotic stroke. (A) Across groups stroke led to a neurological impairment reflected by an increase in mNSS scores at post-stroke (day 1), followed by a slight decrease post-DCS (day 2). (B) The relative mNSS changes from (day 1) to (day 2) did not differ between stimulation groups. (C) Stroke resulted in general impairment in the pasta handling task assessed by the time needed per pasta. (D) Post-intervention contralateral forelimb impairment as indicated by asymmetrical distribution of grasps per pasta between limbs across all groups. (E) Stroke increased atypical behavior counts per pasta in all groups. The 47.8 A/m² DCS group showed the highest counts on (day 2). (F) Analysis of atypical behavior counts from (baseline) to (day 1) revealed no difference between stimulation modalities. mNSS: 0.0 A/m² (n = 6), 0.8 A/m² (n = 5), 31.8 A/m² (n = 8), 47.8 A/m² (n = 7); pasta handling task: 0.0 A/m² (n = 5), 0.8 A/m² (n = 4), 31.8 A/m² (n = 4), 47.8 A/m² (n = 5). mNSS modified neurological severity score, tDCS transcranial direct current stimulation, atypicals atypical behaviors. Data represent mean ± SEM, scatter = individual animals. ^aDifferent from baseline (day -1); ^ttrend towards difference from post-stroke (day 1), *p < 0.05, **p < 0.01.