Table 2.
Relevant MRI acquisition parameters
| Parameter | 3D MP-RAGE | 3D FLAIR | 3D MP2RAGE | |
|---|---|---|---|---|
| HC and early MS | Progressive MS | |||
| Resolution [mm3] | 1.0 × 1.0 × 1.0 | 1.0 × 1.0 × 1.0 | 1.0 × 1.0 × 1.2 | 1.0 × 1.0 × 1.0 |
| Field of view [mm3] | 256 × 256 × 176 | 256 × 256 × 176 | 256 × 256 × 212 | 256 × 256 × 224 |
| Undersampling | GRAPPA × 2 | GRAPPA × 3 | GRAPPA × 3 | CS × 4 |
| TA [min] | 5:30 | 3:17 | 8:22 | 4:35 |
| TI1/TI2 [ms] | 900/– | 1800/– | 700/2500 | |
| TE [ms] | – | 397 | – | |
| Flip angles [°] | 9 | – | 4/5 | |
| TR [s] | 2.3 | 5 | 5 | |
| Bandwidth [Hz/Px] | 240 | 781 | 240 | |
MP-RAGE magnetization-prepared rapid gradient echo; FLAIR fluid-attenuated inversion recovery; MP2RAGE magnetization-prepared 2 rapid gradient echo; TA acquisition time; TI inversion time; TE echo time; TR repetition time; CS compressed sensing