Table 3.
Normothermia versus control: top significant up- and down-regulated DEGs.
| Symbol | Name | logFC | |
|---|---|---|---|
| 1 | C4b | Complement C4B | 2.07 |
| 2 | Klhl40 | Kelch-like family member 40 | 1.80 |
| 3 | Isg15 | ISG15 ubiquitin-like modifier | 1.88 |
| 4 | Serping1 | Serpin family G member 1 | 1.33 |
| 5 | Pou3f4 | POU class 3 homeobox 4 | 2.32 |
| 6 | Rasal2 | RAS protein activator like 2 | 6.80 |
| 7 | Clca4l | Chloride channel calcium activated 4-like | 6.10 |
| 8 | Ifit3 | Interferon-induced protein with tetratricopeptide repeats 3 | 2.22 |
| 9 | Csf2rb | Colony stimulating factor 2 receptor subunit beta | 1.41 |
| 10 | Aebp1 | Adipocyte enhancer-binding protein 1 | 1.26 |
| 11 | Serpine2 | Serpin family E member 2 | 1.19 |
| 12 | Scnn1a | Sodium channel epithelial 1 subunit alpha | 1.50 |
| 13 | Enpp3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3 | 1.42 |
| 14 | Rsl1 | Regulator of sex limited protein 1 | 0.94 |
| 15 | Stat1 | Signal transducer and activator of transcription 1 | 0.87 |
| 16 | Phc3 | Polyhomeotic homolog 3 | 1.15 |
| 17 | Gbp1 | Guanylate-binding protein-1-encoding gene | 1.85 |
| 18 | Parp14 | Poly (ADP-ribose) polymerase family, member 14 | 1.13 |
| 19 | Mx2 | MX dynamin-like GTPase 2 | 1.38 |
| 20 | Hmgcs2 | 3-Hydroxy-3-methylglutaryl-CoA synthase 2 | 1.12 |
| 1 | Kazald1 | Kazal-type serine peptidase inhibitor domain 1 | −1.61 |
| 2 | Sfrp5 | Secreted frizzled-related protein 5 | −2.52 |
| 3 | Aard | Alanine and arginine rich domain containing protein | −1.93 |
| 4 | S100b | S100 calcium-binding protein B | −1.74 |
| 5 | Slc41a3 | Solute carrier family 41, member 3 | −1.96 |
| 6 | Rflnb | Refilin B | −1.19 |
| 7 | Wnt3 | Wnt family member 3 | −3.28 |
| 8 | Sbspon | Somatomedin B and thrombospondin, type 1 domain containing | −1.55 |
| 9 | Car2 | Carbonic anhydrase 2 | −1.18 |
| 10 | Aldh3a1 | Aldehyde dehydrogenase 3 family, member A1 | −0.96 |
| 11 | Otos | Otospiralin | −1.81 |
| 12 | Rapgef3 | Rap guanine nucleotide exchange factor 3 | −1.34 |
| 13 | LOC102550391 | Glutathione S-transferase alpha-3-like | −1.28 |
| 14 | Pde2a | Phosphodiesterase 2A | −1.12 |
| 15 | Cnmd | Chondromodulin | −1.07 |
| 16 | Ippk | Inositol-pentakisphosphate 2-kinase | −1.20 |
| 17 | PDE4C | Phosphodiesterase 4C | −1.12 |
| 18 | HS3ST6 | Heparan sulfate-glucosamine 3-sulfotransferase 6 | −1.45 |
| 19 | TP53I11 | Tumor protein p53 inducible protein 11 | −0.90 |
| 20 | SLC6A13 | Solute carrier family 6 member 13 | −1.38 |
Summary of top up-(red) and down-(blue) regulated genes involved in acute noise response with post-noise normothermia TTM as compared to unexposed control animals. Normo. versus control DEGs. logFC, log fold change.