Table 4.
Hypothermia versus control: top significant up- and down-regulated DEGs.
| Symbol | Name | logFC | |
|---|---|---|---|
| 1 | Cdhr3 | Cadherin-related family member 3 | 3.72 |
| 2 | Dnah6 | Dynein, axonemal, heavy chain 6 | 3.12 |
| 3 | LOC687679 | Similar to small nuclear ribonucleoprotein polypeptide G | 1.15 |
| 4 | Sele | Selectin E | 1.28 |
| 5 | Sec61b | SEC61 translocon subunit beta | 0.72 |
| 6 | Rarres2 | Retinoic acid receptor responder 2 | 0.60 |
| 7 | LOC103694169 | 60S ribosomal protein L39 | 1.66 |
| 8 | Ostc | Oligosaccharyltransferase complex non-catalytic subunit | 0.65 |
| 9 | Nfkbiz | NFKB inhibitor zeta | 0.87 |
| 10 | Agr2 | Anterior gradient 2 | 2.64 |
| 11 | Bst2 | Bone marrow stromal cell antigen 2 | 0.99 |
| 12 | Rassf6 | Ras association domain family member 6 | 0.91 |
| 13 | AABR07026997.1 | 1.00 | |
| 14 | Bola2 | Bola family member 2 | 0.69 |
| 15 | Txn1 | Thioredoxin 1 | 0.86 |
| 16 | Tceal9 | Transcription elongation factor A like 9 | 0.60 |
| 17 | AABR07035791.1 | 2.94 | |
| 18 | Sat1 | Spermidine/spermine N1-acetyl transferase 1 | 0.71 |
| 19 | Prrg1 | Proline-rich and Gla domain 1 | 0.76 |
| 20 | Nbeal1 | Neurobeachin-like 1 | 1.35 |
| 1 | Kcns1 | Kv channel, modifier subfamily S, member 1 | −1.15 |
| 2 | Cntnap4 | Contactin-associated protein family member 4 | −1.01 |
| 3 | Fam78a | Family with sequence similarity 78, member A | −0.92 |
| 4 | Esrrg | Estrogen-related receptor gamma | −0.76 |
| 5 | Zfp804a | Zinc finger protein 804A | −0.82 |
| 6 | Rps6ka2 | Ribosomal protein S6 kinase A2 | −0.60 |
| 7 | Lypd1 | Ly6/Plaur domain containing 1 | −0.81 |
| 8 | Cmya5 | Cardiomyopathy associated 5 | −1.60 |
| 9 | Ky | Kyphoscoliosis peptidase | −1.65 |
| 10 | Fbxo40 | F-box protein 40 | −1.43 |
| 11 | Sv2a | Synaptic vesicle glycoprotein 2a | −1.10 |
| 12 | Ina | Internexin neuronal intermediate filament protein, alpha | −1.02 |
| 13 | Sox8 | SRY-box transcription factor 8 | −0.77 |
| 14 | Cracd | Capping protein inhibiting regulator of actin dynamics | −0.63 |
| 15 | Sgpp2 | Sphingosine-1-phosphate phosphatase 2 | −0.74 |
| 16 | Lypd6 | Ly6/Plaur domain containing 6 | −0.77 |
| 17 | Thbs1 | Thrombospondin 1 | −0.86 |
| 18 | Abcg4 | ATP binding cassette subfamily G member 4 | −0.83 |
| 19 | Map3k13 | Mitogen-activated protein kinase kinase kinase 13 | −0.67 |
| 20 | Rcan2 | Regulator of calcineurin 2 | −0.60 |
Summary of top up- (red) and down-(blue) regulated genes observed with post-noise cochlear hypothermia induction as compared to unexposed control animals. Hypo. versus control DEGs. logFC, log fold change.