Table 1.
Clinico-demographic characteristics of sample, based on macroarea of origin: patients’ characteristics were reported as mean ± SD (or median and interquartile range), and frequency and percentage for continuous and categorical variables, respectively
| North (N = 231) | Center (N = 159) | South (N = 209) | Total (N = 599) | |
|---|---|---|---|---|
| Age, years—mean (SD) | 43.75 (10.80) | 44.02 (11.08) | 44.36 (12.18) | 44.03 (11.36) |
| Sex (F/M) | 136 (58.9%)/95 (41.1%) | 94 (59.1%)/65 (40.9%) | 113 (54.1%)/96 (45.9%) | 343 (57.3%)/256 (42.7%) |
| MS phenotype (PMS/RMS) | 62 (26.8%)/169 (73.2%) | 37 (23.3%)/122 (76.7%) | 89 (42.6%)/120 (57.4%) | 188 (31.4%)/411 (68.6%) |
| DD, years—mean (SD) | 12.26 (8.01) | 11.30 (8.08) | 11.63 (8.02) | 11.79 (8.03) |
| EDSS—median (range) | 4.00 (2.50, 5.88) | 4.50 (2.00, 6.00) | 4.50 (2.00, 6.00) | 4.00 (2.00, 6.00) |
N number, y years, SD standard deviation, MS multiple sclerosis, PMS progressive Multiple Sclerosis, RMS Relapsing Multiple Sclerosis, DD disease duration, EDSS expanded disability status scale