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. 2023 Nov 20;271(2):699–710. doi: 10.1007/s00415-023-12084-4

Table 2.

Time intervals between infusions, analyzed as function of the macroarea of origin

North (N = 231) Center (N = 159) South (N = 209) Total (N = 599)
OCR-ID-PRE-LOCK (∆1), wk—mean (SD) 27.65 (1.65) 28.58 (3.59) 28.20 (2.86) 28.09 (2.73)
∆1 subgroups, N
 ∆1 ≥ 22 and < 26 18 (7.8%) 27 (17.0%) 34 (16.3%) 79 (13.2%)
 ∆1 ≥ 26 and < 30 198 (85.7%) 96 (60.4%) 139 (66.5%) 433 (72.3%)
 ∆1 ≥ 30 15 (6.5%) 36 (22.6%) 36 (17.2%) 87 (14.5%)
OCR-ID-LOCK-PRE-LOCK (∆2), week—mean (SD) 32.32 (6.19) 30.07 (4.72) 29.75 (4.71) 30.83 (5.45)
∆2 subgroups, N
 ∆2 ≥ 22 and < 26 13 (5.6%) 23 (14.5%) 33 (15.8%) 69 (11.5%)
 ∆2 ≥ 26 and < 30 81 (35.1%) 62 (39.0%) 88 (42.1%) 231 (38.6%)
 ∆2 ≥  = 30 137 (59.3%) 74 (46.5%) 88 (42.1%) 299 (49.9%)

N number; wk weeks; SD standard deviation; OCR Ocrelizumab; PRE-LOCK OCR cycle occurred between August and December 2019; ID-PRE-LOCK time interval, in weeks, between all the infusions prior to the pre-lock cycle; LOCK OCR cycle following pre-lock cycle, between February and June 2020; ID-LOCK-PRE-LOCK time interval, in weeks, between the pre-lock and the lock cycle