Table 2.
North (N = 231) | Center (N = 159) | South (N = 209) | Total (N = 599) | |
---|---|---|---|---|
OCR-ID-PRE-LOCK (∆1), wk—mean (SD) | 27.65 (1.65) | 28.58 (3.59) | 28.20 (2.86) | 28.09 (2.73) |
∆1 subgroups, N | ||||
∆1 ≥ 22 and < 26 | 18 (7.8%) | 27 (17.0%) | 34 (16.3%) | 79 (13.2%) |
∆1 ≥ 26 and < 30 | 198 (85.7%) | 96 (60.4%) | 139 (66.5%) | 433 (72.3%) |
∆1 ≥ 30 | 15 (6.5%) | 36 (22.6%) | 36 (17.2%) | 87 (14.5%) |
OCR-ID-LOCK-PRE-LOCK (∆2), week—mean (SD) | 32.32 (6.19) | 30.07 (4.72) | 29.75 (4.71) | 30.83 (5.45) |
∆2 subgroups, N | ||||
∆2 ≥ 22 and < 26 | 13 (5.6%) | 23 (14.5%) | 33 (15.8%) | 69 (11.5%) |
∆2 ≥ 26 and < 30 | 81 (35.1%) | 62 (39.0%) | 88 (42.1%) | 231 (38.6%) |
∆2 ≥ = 30 | 137 (59.3%) | 74 (46.5%) | 88 (42.1%) | 299 (49.9%) |
N number; wk weeks; SD standard deviation; OCR Ocrelizumab; PRE-LOCK OCR cycle occurred between August and December 2019; ID-PRE-LOCK time interval, in weeks, between all the infusions prior to the pre-lock cycle; LOCK OCR cycle following pre-lock cycle, between February and June 2020; ID-LOCK-PRE-LOCK time interval, in weeks, between the pre-lock and the lock cycle