Table 3.

Clinico-demographic characteristics, based on OCR interval dosing: patients’ characteristics were reported as mean ± SD (or median and interquartile range)

	RMS-SID (n = 364)	RMS-EID (n = 353)	P
Age, year—mean (SD)	40.59 (10.56)	42.23 (10.92)	n.s
Sex (F/M)	236/128	227/126	n.s
Macroregion (N/C/S)	132/118/114	160/113/80	n.s
DD, year—mean (SD)	10.84 (7.94)	11.56 (8.72)	n.s
EDSS—median (range)	2.5 (0–7)	3 (0–7)	n.s
Previous OCR inf—mean (SD)	2.21 (1.47)	1.78 (0.91)	0.007
Delta PRE-LOCK OCR inf, wk—mean (SD)	28.04 (3.75)	29.03 (4.18)	n.s

Bold: significant results

n number; y years; wk weeks; SD standard deviation; RMS relapsing multiple sclerosis; SID standard interval dosing; EID extended interval dosing; DD disease duration; EDSS expanded disability status scale; PRE-LOCK OCR cycle occurred between August and December 2019; ID-PRE-LOCK time interval, in weeks, between all the infusions prior to the pre-lock cycle; P Bonferroni-adjusted P-values