TABLE 1.
Evolution of titer and prevalence of CFA and paramyosin-reactive IgG4 in W. bancrofti-parasitized individuals before and after filaricidal drug treatments
| Time (mo) after treatment | Meana CFA level (range) | % Residual antigen levelb | Meana paramyosinreactive IgG4 titer (range) | % Residual paramyosin-reactive IgG4b |
|---|---|---|---|---|
| 0c | 1,874 (100–8,778) | 100 | 704 (26–7,742) | 100 |
| 12 | 713 (0–8,124) | 51 | 221 (5–2,267) | 37 |
| 24 | 479 (0–7,816) | 35 | 111 (5–1,763) | 24 |
a
Geometric mean.
b
Arithmetic mean of individual residual antigen levels or IgG4 titers.
c
Before the first treatment (see Materials and Methods).