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. 2023 Jun 12;46(1):969–980. doi: 10.1007/s11357-023-00842-1

Table 1.

Baseline characteristics of SLAS study participants (N = 4551) by curry consumption levels at baseline

Never or rarely Occasional Often Very Often Daily Crude Adjusted*
Never or < once/year  > once/year, < once/month  > once/month, < once/week  > once/week, not daily  ≥ once daily p P
N of participants 828 2060 1006 514 143
Sex: Women 68.5 (567) 66.1 (1361) 60.4 (608) 52.5 (270) 52.5 (81)  < 0.001c
Age, years 68.1 ± 8.2 65.9 ± 7.3 65.6 ± 7.3 64.9 ± 7.2 66.8 ± 7.6 0.001b
Ethnicity: Chinese 97.0 (803) 94.4 (1945) 90.3 (908) 72.9 (375) 63.6 (91)
Malay, Indian and Other 3.0 (25) 5.6 (115) 9.8 (98) 27.1 (139) 36.4 (52)  < 0.001c
Education: 0 years 28.1 (233) 16.3 (336) 13.8 (139) 13.4 (69) 23.8 (34)  < 0.001
  1–6 years 41.2 (341) 38.8 (800) 34.3 (345) 33.7 (173) 41.3 (59)
  > 6 years 30.7 (254) 44.9 (924) 51.9 (522) 52.9 (272) 35.0 (50)
Housing: 1–2 room 17.3 (143) 14.3 (294) 10.4 (105) 19.1(98) 19.6 (28)  < 0.001
  3-room 30.0 (248) 26.4 (543) 25.0 (252) 24.3 (125) 30.8 (44)
  4 + room and private 52.8 (437) 59.4 (1223) 64.5 (649) 56.6 (291) 49.7 (71)
Single/divorced/widowed 36.8 (305) 30.0 (617) 27.0 (272) 33.1 (170) 31.5 (45)  < 0.001
Instrumental support (0–13) 29.7 (246) 23.8 (490) 21.0 (211) 24.9 (128) 25.2 (36)  < 0.001
  (14–15) 36.2 (300) 37.5 (772) 35.2 (354) 35.6 (183) 36.4 (52)
  (16–17) 34.1 (282) 38.7 (798) 43.8 (441) 39.5 (203) 38.5 (55)
Smoking: Past smoker 11.7 (97) 8.8 (181) 11.5 (116) 13.2 (68) 11.2 (16)  < 0.001
Current smoker 7.2 (60) 7.6 (156) 6.3 (63) 11.9 (61) 9.8 (14)
Alcohol >  = once /week 4.5 (37) 3.6 (74) 5.3 (53) 6.4 (33) 5.6 (8) 0.024
Physical activity score 2.18 ± 1.75 2.35 ± 1.68 2.32 ± 1.79 2.35 ± 1.80 1.92 ± 1.61 0.004
Social activity score 2.85 ± 2.51 3.17 ± 2.46 3.27 ± 2.48 3.11 ± 2.49 2.48 ± 2.07 0.001
Productive activity score 3.72 ± 1.92 3.87 ± 1.82 4.12 ± 1.90 3.98 ± 1.91 3.59 ± 1.77 0.001
Medical comorbidities count 2.45 ± 1.58 2.33 ± 1.47 2.37 ± 1.47 2.36 ± 1.52 2.62 ± 1.47 0.018b 0.349a
Cardiovascular diseases 13.0 (108) 11.0 (226) 10.7 (108) 10.7 (55) 12.6 (18) 0.483 0.830
Hypertension 64.1 (531) 59.7 (1229) 62.8 (632) 64.0 (329) 65.0 (93) 0.090 0.568
Central obesity 47.9 (397) 52.6 (1083) 53.3 (536) 56.2 (289) 55.9 (80) 0.003c 0.026
Diabetes 16.2 (134) 14.7 (302) 14.9 (150) 15.8 (81) 26.6 (38) 0.001c 0.316
Metabolic syndrome 43.0 (356) 47.5 (978) 46.3 (466) 47.9 (246) 53.1 (76) 0.045 0.022
COPD (FEV1/FVC < 0.70) 22.9 (190) 17.8 (366) 18.3 (184) 14.6 (75) 15.4 (22)  < 0.001c 0.305
Depression (GDS ≥ 5, treatment) 9.8 (41) 5.8 (60) 3.6 (29) 7.6 (30) 7.7 (21)  < 0.001 0.030
Cognitive impairment (MMSE < 23) 13.0 (108) 6.0 (123) 6.2 (62) 9.3 (48) 15.4 (22)  < 0.001 0.008
Chronic kidney disease 5.6 (46) 4.1 (84) 5.2 (52) 5.1 (26) 5.6 (8) 0.410 0.905
Cancer 2.1 (17) 2.7 (56) 2.6 (26) 1.6 (8) 0.7 (1) 0.305 0.417
Gastro-intestinal conditions 5.9 (49) 6.9 (142) 6.3 (63) 5.4 (28) 7.0 (10) 0.727 0.661
Musculoskeletal conditions 19.2 (159) 16.1 (331) 17.7 (178) 17.2 (88) 15.4 (22) 0.330 0.302
GDS score 1.44 ± 2.33 1.00 ± 1.82 1.07 ± 2.04 1.14 ± 2.16 1.75 ± 2.81  < 0.001b 0.001b
MMSE score 26.9 ± 3.5 27.9 ± 2.6 27.9 ± 2.6 27.8 ± 3.0 26.6 ± 3.4  < 0.001b 0.001b
FEV1/Ht, L/m 1.05 ± 0.30 1.15 ± 0.30 1.15 ± 0.31 1.18 ± 0.33 1.05 ± 0.33  < 0.001b 0.002b
Albumin 42.1 ± 3.0 42.4 ± 2.7 42.5 ± 2.6 42.5 ± 2.4 42.1 ± 3.2 0.001b 0.095b
Haemoglobin 13.3 ± 1.3 13.4 ± 1.4 13.5 ± 1.3 13.7 ± 1.5 13.4 ± 1.5  < 0.001b 0.178b
eGFR 119.3 ± 40.5 113.0 ± 37.9 115.7 ± 41.5 113.1 ± 40.7 109.7 ± 38.0 0.001a 0.009b
Waist circumference (men) 86.9 ± 9.8 88.1 ± .5 88.4 ± 8.4 88.9 ± 10.2 91.4 ± 11.5 0.011a 0.029a
Waist circumference (women) 80.2 ± 10.1 81.7 ± 9.9 81.9 ± 9.7 83.9 ± 10.6 82.8 ± 12.0  < 0.001a 0.016b
Sitting SBP 131.0 ± 16.7 129.2 ± 15.5 131.1 ± 16.2 130.8 ± 16.8 130.7 ± 14.9 0.006b 0.022b
Sitting DBP 80.1 ± 10.1 80.6 ± 9.6 81.6 ± 9.5 82.3 ± 8.9 81.0 ± 10.3 0.001b 0.068b
Fasting blood glucose, mmol/L 5.31 ± 1.58 5.35 ± 1.51 5.40 ± 1.51 5.48 ± 1.61 5.83 ± 2.37 0.002a 0.050b
TyG 9.19 ± 0.54 9.23 ± 0.53 9.25 ± 0.53 9.25 ± 0.55 9.28 ± 0.61 0.009a 0.122b
AIP = Log (TG/HDLc) –0.08 ± 0.27 –0.06 ± 0.27 –0.05 ± 0.26 –0.04 ± 0.27 –0.05 ± 0.29 0.018a 0.044b
CRI-I = TChol/HDL-Chol 3.84 ± 1.06 3.85 ± 1.00 3.94 ± 1.00 3.96 ± 1.03 3.92 ± 1.25 0.006a 0.289b
CRI-II = LDLc/HDLc 2.37 ± 0.87 2.37 ± 0.80 2.45 ± 0.82 2.46 ± 0.82 2.42 ± 0.97 0.011a 0.205b
LMR 5.21 ± 2.45 5.33 ± 2.63 5.30 ± 1.88 5.11 ± 1.75 5.46 ± 1.91 0.242a 0.304b
NLR 1.83 ± 0.85 1.80 ± 0.84 1.75 ± 0.87 1.79 ± 0.76 1.65 ± 0.73 0.018a 0.091a
PLR 137.5 ± 55.1 139.9 ± 56.3 135.6 ± 53.4 133.4 ± 53.0 118.4 ± 40.0  < 0.001a 0.012b
SII index 460.4 ± 269.4 458.9 ± 276.9 442.6 ± 263.5 456.3 ± 228.5 404.5 ± 199.8 0.022a 0091b

Figures shown are percentage (number) or mean ± SD

COPD: self-report or FEV1/FVC < 0.70; Chronic kidney disease; self-report or eGFR < 60 ml/min/1.73 m; Low HDL-Chol: HDL-Chol < 1.03 (male) or < 1.29 (female)

ANOVA: alinear-p; bquadratic-p; Chi-squared: clinear

*Adjusted for age, sex and ethnicity, education, housing, marital status, social support, smoking, alcohol, physical, social and productive activity

GDS: Geriatric Depression Scale; MMSE: Mini Mental State Examination; eGFR: estimated glomerular filtration rate;

TyG: Triglyceride-glucose index (TyG) = Ln(TG × FBG/2) calculated using mg/dl concentrations of fasting TG and FBG

AIP: Atherogenic Index of Plasma = log10 (TG/HDLc), CRI-1: Castelli Risk Index-1 = TC/HDLc; CRI-II: Castelli Risk Index-2 = HDLc/LDLc;

NLR: neutrophil–lymphocyte ratio, LMR: lymphocyte-monocyte ratio, PLR: platelet-lymphocyte ratio, SII index: systemic and immune inflammation index