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. 2023 Nov 22;46(2):2503–2519. doi: 10.1007/s11357-023-01014-x

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© The Author(s), under exclusive licence to American Aging Association 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 5 — Classification and density of microglia morphology with age and related cognitive impairment. a Example images displaying ramified and hypertrophic morphology as well as C1q + or C1q − . b–e Ramified C1q − , ramified C1q + , hypertrophic C1q − , and hypertrophic C1q + microglia density did not change with age (p > 0.05). f–i Microglial morphology and C1q expression did not change with cognitive impairment (p > 0.05)