Fig. 7.

Relation between pathological and inflammatory factors and the amyloid-beta (Aβ) burden of the temporal (TCx) and parietal (PCx) cortices. This analysis was performed in cognitively unimpaired (CU; blue scatter plots, a–d) and in Alzheimer’s disease (AD; red scatter plots, e–n) donors. Protein concentrations were measured in ng/mg or pg/mg and normalized. Significance was determined for p-values less than 0.05. Regression lines are shown with the 95% confidence interval for the significant relation between Aβ burden and protein concentrations. Results remained significant after correction for age, sex and education years