Table 3.

Relation between the cortical amyloid burden and education years in normal cognition and Alzheimer’s disease

Region of interest	Cognitively unimpaired				Alzheimer’s disease
	Unadjusted model		Adjusted model		Unadjusted model		Adjusted model
	β (SE)	p value	β (SE)	p value	β (SE)	p value	β (SE)	p value
TCx total	− 0.22 (0.19)	0.254	− 0.08 (0.20)	0.689	− 0.15 (0.39)	0.699	− 0.20 (0.44)	0.655
TCx GM	− 0.31 (0.22)	0.177	− 0.17 (0.24)	0.486	− 0.65 (0.50)	0.219	− 0.69 (0.57)	0.249
TCx WM	− 0.12 (0.04)	0.013	− 0.09 (0.04)	0.048	0.05 (0.11)	0.651	0.05 (0.12)	0.665
PCx total	− 0.17 (0.12)	0.169	− 0.17 (0.13)	0.207	0.08 (0.29)	0.775	0.05 (0.29)	0.868
PCx GM	− 0.18 (0.16)	0.288	− 0.18 (0.17)	0.319	− 0.09 (0.41)	0.834	− 0.12 (0.43)	0.785
PCx WM	− 0.16 (0.05)	0.008	− 0.15 (0.06)	0.012	− 0.08 (0.14)	0.593	− 0.10 (0.12)	0.400

Multiple regression modeling was used to adjust for potential contributions of age and sex

TCx temporal cortex, PCx parietal cortex, GM gray matter, WM white matter, β standardized β coefficient, SE standard error

Significant p values (< 0.05) are highlighted in bold