Fig. 7.

Effects of three polyphenols in Tau784 mice. A mixture of catechin, chlorogenic acid, and rutin or catechin alone was orally administered to 8–10-month-old Tau784 mice (mean body weight, 32.0 g) for 1 month. The doses corresponded to those contained in 30 μg simple crush powder of Mamaki fruits: 0.087 μg catechin, 0.036 μg chlorogenic acid, and 0.123 μg rutin. The three-polyphenol mixture improved mouse memory incompletely, and catechin alone had an even weaker effect