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. 2023 Aug 31;46(2):1543–1560. doi: 10.1007/s11357-023-00917-z

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© The Author(s), under exclusive licence to American Aging Association 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 5 — Normalized perturbation scores for KEGG pathways from a pathway impact analysis per intervention-by-sex group. Shown are pathways that were significantly (adjusted p ≤ 0.05; indicated by an asterisk) predicted to be impacted by at least three interventions regardless of sex in A liver and B kidney tissues (no pathways met these criteria in muscle samples)