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. 2024 Jan 30;14:2534. doi: 10.1038/s41598-024-53173-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Bacterial abundance patterns of the R and NR groups before and after UDCA/CDCA treatment. A repeated measures analysis of variance (ANOVA) was performed to analyze the differences. (Blue dot: the responder group (R), orange dot: the non-responder group (NR), asterisk (*): significant in cross-sectional analysis (p < 0.05), solid line: significant in longitudinal analysis (p < 0.05), dash line: Not significant in longitudinal analysis (p > 0.05)). (A) Relative abundance of the Erysipelotrichi lineage. (B) Relative abundance of the Firmicutes phylum. (C) Relative abundance of the Rikenellaceae and Odoribacteraceae families.