Table 3.
Cross-sectional analysis of the relationship between ABI score decrease (tenths*) and worse cognitive performance, stratified by gender females
Variable | ABI < 0.8 | ABI between 0.8– < 1.1 | ABI between > 1.1–1.4 | All | ||||
---|---|---|---|---|---|---|---|---|
p-value | Beta (95% CI) | p-value | Beta (95% CI) | p-value | Beta (95% CI) | p-value | Beta (95% CI) | |
MMSE (total score) | 0.0100 | 0.603 (0.146, 1.060) | 0.0197 | 0.362 (0.059, 0.666) | 0.0311 | 0.282 (0.026, 0.538) | 0.7566 | 0.028 (− 0.151, 0.208) |
Cumulative Executive Dysfunction Index | 0.0290 | − 0.367 (− 0.696, − 0.038) | 0.0223 | − 0.255 (− 0.473, − 0.037) | 0.0336 | − 0.199 (− 0.383, − 0.016) | 0.4279 | − 0.052 (− 0.181, 0.077) |
7-MT (total score) | 0.0036 | 0.429 (0.142, 0.717) | 0.0005 | 0.343 (0.152, 0.533) | 0.0023 | 0.252 (0.091, 0.413) | 0.3529 | 0.054 (− 0.060, 0.169) |
7-MT (Clock Drawing Test) | 0.0315 | 0.159 (0.014, 0.304) | 0.0123 | 0.122 (0.027, 0.217) | 0.0412 | 0.084 (0.004, 0.165) | 0.9510 | 0.002 (− 0.055, 0.059) |
7-MT (free and facilitated memory) | 0.0056 | 0.183 (0.054, 0.312) | 0.0046 | 0.124 (0.039, 0.210) | 0.0120 | 0.093 (0.021, 0.165) | 0.6838 | 0.011 (− 0.040, 0.061) |
7-MT (verbal fluency) | 0.1592 | 0.098 (− 0.038, 0.234) | 0.0236 | 0.104 (0.014, 0.195) | 0.0728 | 0.070 (− 0.006, 0.146) | 0.6197 | 0.014 (− 0.040, 0.067) |
7-MT (Benton’s Temporal Orientation Test) | 0.9397 | 0.002 (− 0.049, 0.053) | 0.8702 | − 0.003 (− 0.037, 0.031) | 0.8462 | − 0.003 (− 0.031, 0.026) | 0.6094 | − 0.005 (− 0.025, 0.015) |
Denomination | 0.7134 | 0.017 (− 0.074, 0.108) | 0.5913 | 0.017 (− 0.044, 0.077) | 0.9137 | 0.003 (− 0.048, 0.054) | 0.2549 | − 0.021 (− 0.057, 0.015) |
Immediate memory | 0.9456 | 0.004 (− 0.116, 0.125) | 0.7700 | − 0.012 (− 0.092, 0.068) | 0.9047 | − 0.004 (− 0.071, 0.063) | 0.9552 | 0.001 (− 0.046, 0.048) |
Total short-term memory | 0.0056 | 0.327 (0.096, 0.558) | 0.0046 | 0.222 (0.069, 0.376) | 0.0121 | 0.166 (0.037, 0.295) | 0.6830 | 0.019 (− 0.072, 0.110) |
Free short-term memory | 0.0004 | 0.653 (0.293, 1.014) | 0.0004 | 0.433 (0.194, 0.673) | 0.0012 | 0.334 (0.132, 0.536) | 0.4208 | 0.059 (− 0.084, 0.201) |
Facilitated short-term memory | 0.0533 | − 0.342 (− 0.689, 0.004) | 0.0597 | − 0.222 (− 0.452, 0.009) | 0.0710 | − 0.179 (− 0.373, 0.015) | 0.4883 | − 0.048 (− 0.184, 0.088) |
Total long-term memory | 0.0693 | 0.213 (− 0.016, 0.442) | 0.0107 | 0.199 (0.047, 0.352) | 0.0145 | 0.161 (0.032, 0.289) | 0.0515 | 0.089 (0.000, 0.179) |
Free long-term memory | 0.0095 | 0.558 (0.137, 0.979) | 0.0013 | 0.460 (0.181, 0.740) | 0.0018 | 0.377 (0.141, 0.612) | 0.0249 | 0.189 (0.024, 0.354) |
Facilitated long-term memory | 0.0874 | − 0.345 (− 0.740, 0.050) | 0.0517 | − 0.261 (− 0.524, 0.001) | 0.0558 | − 0.216 (− 0.437, 0.005) | 0.2057 | − 0.100 (− 0.254, 0.055) |
Hole Peg Test (dominant hand) | 0.2781 | − 0.659 (− 1.848, 0.530) | 0.0667 | − 0.741 (− 1.530, 0.049) | 0.0893 | − 0.578 (− 1.244, 0.087) | 0.1473 | − 0.354 (− 0.831, 0.124) |
*tenths = 0.1. MMSE, Mini-Mental State Examination; 7-MT, 7-min test, Significant effect in bold (p < 0.05)