Table 1.

Scalable vs. genome-wide screen parameters.

	Scalable screens	Genome-wide screens	Genome-wide screens (Olivieri)
Compounds	BTZ, HU, CPT, OLA, COL	CPT, OLA, COL	HU, CPT, OLA
Dosage	IC20	IC50	IC20a
Timepoints	T6, T9, T12, T15, T18	T18	T18
Coverage	1000×	250×	250–400×
Replicates	Triplicates	Triplicates	Duplicates
Cell line	RPE-1 hTERT p53-/-	HAP1	RPE-1 hTERT p53-/-

^aDetermined over 12 days instead of 3 days.