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Expression of matrix and marker proteins in the bone defect after gel-scaffold construct implantation. (a) Masson's trichrome staining images of cranial defects after the implantation of scaffold constructs for 4 and 8 weeks. (b) OCN immunohistochemical staining images of cranial defects after the implantation of scaffold constructs for 4 and 8 weeks. (c and d) Quantitative analysis of OCN immunohistochemical staining for 4 and 8 weeks. *p < 0.05, **p < 0.01, and ***p < 0.001.
