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A schematic molecular view of cancer chemoprevention by anthocyanidins. Anthocyanidins may contribute to cancer chemoprevention through targeting three different signal transduction pathways and downstream genes. Abbreviations: AP-1, activator protein-1; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; LPS, lipopolysaccharide; NF-κB, nuclear factor κB; ROS, reactive oxygen species; TPA, 12-O-tetradecanoylphorbol-13-acetate.
