Table 1.

Data summary for 23 cats with non-ocular melanoma

Case	Breed	Sex	Age (years)	Site of origin	Presenting complaint	Benign/malignant	Histologic type	Treatment	Survival (days)	Cause of death	Necropsy	Recurrence or mets	Junctional activity
1	DSH	FS	4	Ventral to left nares	Dark, pigmented, Firm, solid	Benign	Epithelial	SX	368	NA—alive	NA—alive	No	No
2	Siam	M	13	Dorsal neck	Small black tumour, non-tender, fast growing	Benign	Epithelial	SX	LTF@181	LTF	LTF	No	No
3	NK	NK	10	Right pinna	Acute onset of growth	Benign	Spindle	SX	564	NA—alive	NA—alive	No	No
4	DSH	F	NK	Right dorsolateral lumbar region	Unknown	Benign	Epithelial	SX	725	NA—alive	NA—alive	No	Yes
5	DHC	F	17	Back of right ear	Growth came up in last 3–4 months	Benign	Spindle	SX	LTF	LTF	LTF	LTF	Yes
6	DSH	MC	6	Left pinna	Small skin growth noted at time of dental	Benign	Epithelial	SX	364	Sudden death unrelated to tumour	Myocardial-endocardial fibrosis	No	Yes
7	Silver Tabby	FS	15	Dorsal muzzle, caudal to nose	Previous diagnosis of apocrine cysts, recurrent	Benign	Epithelial	SX	1003	Euthanasia unrelated to tumour	Not done	No	Yes
8	DLH	FS	14	Left front 5th digit	Erythema and alopecia over digit	Benign	Spindle	SX, carboplatin	356	Euthanasia related to tumour	Not done	Suspected recurrence and solitary lung met; no histopath confirmation	Yes
9	DSH	F	12	Dorsum of head	Slow-growing black dermal mass	Benign	Spindle	SX	969	Euthanasia unrelated to tumour	Not done	No	No
10	DSH	MC	11	Plantar surface of left rear limb	Fast growing subcutaneous mass	Malignant	Spindle	Mid-femoral amputation	577	NA–alive	NA—alive	No	Yes
11	DSH	F	17	Digit, left front paw	Non-weight bearing left forelimb, lytic lesion on X-rays, painful	Malignant	Balloon cell	Euthanasia	0	Euthanasia related to tumour	Hepatic nodules and uterine polyps	Metastasis to liver	Cannot be determined
12	DSH	FS	12	Right ear margin	Lump on ear	Malignant	Spindle	SX	422	Euthanasia related to tumour	Not done	Recurrence and lymph node metastasis	Cannot be determined
13	DSH	FS	3	Palmar surface of left front foot	Owner noticed blood on bed	Malignant	Epithelial	SX	LTF@275	LTF	LTF	LTF	Yes
14	DSH	FS	9.5	Dorsum, above shoulder	1 month duration with slow growth	Malignant	Epithelial	SX	674	NA—alive	NA—alive	No	Yes
15	DLH	MC	11	Left external nares	Inflammatory lesion of several months duration	Malignant	Epithelial	SX	40	Euthanasia	Not taken	No	Yes
16	DSH	FS	18	Lateral thorax	Large mass on thorax	Malignant	Spindle	SX	16	NA—alive	NA—alive	No	Yes
17	DSH	FS	18	Nasal planum	Rapidly growing and bleeding mass	Malignant	Spindle	SX	LTF@205	LTF	LTF	Local recurrence at 4 and 6 months	Yes
18	Maine coon	FS	2	Right lateral thigh	Recurrent after excision	Malignant	Epithelial	SX, RTX d0,7,21, doxorubicin, carboplatin, melphalan	122	Euthanasia—progressive dz	Not done	Multiple skin masses and inguinal lymphadenopathy	No
19	DLH	FS	12	Right forepaw large pad	Recurrent after sx, prescap lymph node metastasis, anorexia, lethargy	Malignant	Epithelial	SX originally, carboplatin approx. 140 d after sx	Approx. 150	Euthanasia—progressive dz	Mets to prescap In, liver, spleen, no evidence of dz on foot pad	Mets to prescap In, liver, spleen, recurrent after original sx	No
20	DLH	FS	10	Oral mass-maxillary	Recurrence and pulmonary metastasis	Malignant	Epithelial	SX originally, carboplatin approx 195 d after sx; Taxol®	Approx. 365	Progressive dz	Not done	Multiple skin and lung masses, palpable renal masses, midabd mass palpable	Yes
21	NK	MC	7	Unknown skin location	Skin mass found during grooming	Benign	Epithelial	SX	Alive	NA—alive	NA—alive	No	Yes
22	Maine coon	FS	12	Oral mass-maxillary	Mass detected at routine dental prophylaxis	Benign	Epithelial	Radiation therapy, chemotherapy pending	Alive	NA—alive	NA—alive	No	No
23	DSH	MC	10	Oral mass-maxillary	Mass detected at routine dental prophylaxis	Malignant	Spindle	Radiation therapy	Alive	NA—alive	NA—alive	Large recurrent/progressive mass	Yes

DSH, domestic short hair. DLH, domestic long hair. Siam, Siamese. NK, not known. F, female. M, male. LTF, lost to follow-up. NA, not applicable. SX, surgery