Table 1.
Characteristics of study population (Black children of the URECA cohort)
| Combined sample (n=262) | Children with asthma at age 7 (n=85) | Children without asthma by age 7 (n=177) | OR (95% CI) | p-value | |
|---|---|---|---|---|---|
| Sex (male) | 129 (49%) | 48 (56%) | 81 (46%) | 1.53 (0.91-2.59) | 0.11 |
| Mother has asthma | 117 (45%) | 47 (55%) | 70 (40%) | 1.89 (1.12-3.19) | 0.017 |
| Father has asthma | 80 (30%) | 28 (33%) | 52 (29%) | 1.18 (0.68-2.06) | 0.56 |
| Cesarean section delivery | 77 (29%) | 28 (33%) | 49 (28%) | 1.28 (0.73-2.25) | 0.38 |
| Breastfeeding | 135 (52%) | 46 (54%) | 81 (46%) | 1.40 (0.83-2.35) | 0.21 |
| Age of mother at time of birth (y) | 24±5.7 | 24.7±6.3 | 23.7±5.3 | 1.02(0.98-1.08) | 0.21 |
| No. of hours/week of day care in y1 | 13.3±18.6 | 14.5±19.4 | 12.7±18.3 | 1.01 (0.99-1.02) | 0.47 |
| No. of children in home | 1.32±1.56 | 1.38±1.79 | 1.30±1.44 | 1.03 (0.88-1.22) | 0.71 |
| Cord blood cotinine detected1 | 44 (18%) | 19 (23%) | 25 (16%) | 4.3 (0.97-19) | 0.055 |
| Atopy2 | 166 (63%) | 63 (74%) | 103 (58%) | 2.06 (1.16-3.64) | 0.013 |
| FEV1 % predicted3 | 101.3±14.9 | 100.5±15.9 | 101.7±14.5 | 0.99 (0.97-1.02) | 0.60 |
| FEV1/FVC4 | 0.82±0.08 | 0.81±0.08 | 0.83±0.07 | 0.12 (0.002-7.85) | 0.32 |
| Asthma controller medication in the past 12 months5 | 34 (13%) | 27 (31%) | 7 (4%) | 10.64 (4.39-25.75) | NA |
| Albuterol use in the past 12 months5 | 86 (34%) | 71 (84%) | 15 (9%) | 51.4 (23.5-112.2) | NA |
| Prednisone in the past 12 months5 | 54 (21%) | 35 (41%) | 19 (11%) | 5.45 (2.86-10.38) | NA |
Values are counts (percentages) or means ± SDs,
1
available for 242 children,
2
positive for at least one serum or skin test for aeroallergen-specific IgE at age 7,
3
measured in 175 children,
4
measured in 177 children,
5
available for 252 children.
OR: odds ratio for asthma, NA: not applicable