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Proposed grading system for oral squamous cell carcinoma (OSCC) using tumour budding[17]
| Score | |
|---|---|
| Tumour budding activity (BA)/10 HPF | |
| No budding | 1 |
| <15 budding foci | 2 |
| >15 budding foci | 3 |
| Smallest cell nest size (CNS)/10 HPF | |
| >15 cells | 1 |
| 5-15 cells | 2 |
| 2-4 cells | 3 |
| Single-cell invasion | 4 |
| Tumour Grading | |
| Well-differentiated (G0) | 2-3 |
| Moderately differentiated (G1) | 4-6 |
| Poorly differentiated (G2) | 7 |
