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. 2024 Jan 31;21:3. doi: 10.1186/s12989-024-00565-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — RT-qPCR results of selected cancer-associated genes in tumors induced by MWCNTs or amosite asbestos. As compared to the control peritoneal tissues, mRNA expression was downregulated in Hrasls, Nr4a1, Fgfr4 and Ret (A–D) or upregulated in Rnd3 and Gadd45b (E, F) in all or most of 36 tumors. Scatter dot plots and statistical results were obtained using GraphPad Prism 9. Statistical significance was determined at P < 0.05, t–test for unpaired values, two-tailed. Bar depicts mean and standard error of the mean (SEM). Asterisks depict statistical significance at **** (P < 0.0001), *** (P < 0. 001), **(P < 0. 01), * (P < 0. 05)