FIGURE 1.

Platelet concentrate (PC) preparation methods. There are three schemes of platelet preparation established, buffy‐coat (BC) PC, platelet‐rich plasma (PRP) PC and apheresis PC production (top, middle and bottom). ¹⁷ , ¹⁸ BC is first separated from whole blood by hard spin and then pooled with plasma or platelet additive solutions (PAS), where remanent red blood cells are removed under soft centrifugation. On the contrary, PRP is isolated by soft spin. Subsequently, platelets are segregated via hard centrifugation. As for apheresis PC, automated blood cell separator is utilized to collect platelets and transfuse back the other blood components into donors. BC and apheresis platelets can be resuspended in PAS and leukoreduction (LR) technique can be applied.