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. 2023 Dec 26;5(1):101348. doi: 10.1016/j.xcrm.2023.101348

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© 2024 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Adipose tissue displays a differential transcriptomic response to exercise in individuals with NGT and T2D

(A) Experimental design.

(B) Heatmap of differentially expressed genes in adipose tissue from individuals with normal glucose tolerance (NGT; n = 20) or type 2 diabetes (T2D; n = 28) analyzed between pre- and post-exercise or recovery conditions.

(C) Overlay of significantly differentially expressed genes between pre- and post-exercise in adipose tissue of participants with NGT or T2D.

(D) Overlay of significantly differentially expressed genes between pre-exercise and recovery in adipose tissue of individuals with either NGT or T2D.

(E) Visualization of the main pathways’ clusters derived from the GO hierarchy pathway analysis. Color of the circles indicates the condition in which the pathways are significantly altered.