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. 2023 Dec 26;5(1):101348. doi: 10.1016/j.xcrm.2023.101348

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© 2024 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Exercise induces the expression of genes encoding for secreted proteins, with a stronger effect in recovery

(A) Percentage of the genes encoding for secreted proteins from the total number of genes significantly altered in individuals with either NGT (blue) or T2D (purple) between the post- and pre-exercise conditions.

(B) Volcano plots showing log fold change (logFC) and significance of genes encoding for secreted proteins identified in (A).

(C) Overlay of genes identified in adipose tissue from individuals with NGT or T2D encoding for secreted proteins altered post-exercise.

(D) Percentage of the genes encoding for secreted proteins of the total genes significantly altered in adipose tissue from individuals with NGT (light blue) or T2D (pink) between the pre-exercise and recovery conditions.

(E) Volcano plots showing logFC and significance of genes encoding for secreted proteins identified in (D).

(F) Overlay of genes identified in adipose tissue from individuals with either NGT or T2D encoding for secreted proteins that are altered at recovery.

(G) Heatmap of gene expression profile of selected adipokines identified pre- and post-exercise and recovery in adipose tissue from individuals with either NGT or T2D. The color scale represents mean scale CPM.