. Author manuscript; available in PMC: 2024 Jun 1.

Published in final edited form as: Pediatrics. 2023 Jun 1;151(6):e2022059013. doi: 10.1542/peds.2022-059013

TABLE 2.

Adjusted IRR and 95% CI of Country-Level Pediatric ART Coverage (%) and AIDS-related Deaths (Per 100 000 Population) Before and After National “Treat All” Adoption, 2010–2020

UNAIDS Regions	Pediatric ART Coverage		Pediatric AIDS Mortality
UNAIDS Regions	adj.IRR (95% CI)	P	adj.IRR (95% CI)	P
Global	0.94 (0.91–0.98)^a	.001^a	1.08 (1.05–1.11)^a	<.001^a
Asia-Pacific	0.94 (0.79–1.12)	.459	1.26 (1.07–1.49)^a	.007^a
Caribbean	0.94 (0.84–1.05)	.248	1.04 (1.01–1.06)^a	.005^a
East and Southern Africa	0.91 (0.87–0.95)^a	<.001^a	1.10 (1.05–1.14)^a	<.001^a
Latin America	0.99 (0.94–1.05)	.812	1.04 (0.97–1.10)	.324
Middle East and North Africa	1.03 (0.86–1.21)	.786	0.97 (0.79–1.19)	.782
West and Central Africa	0.93 (0.87—0.99)^a	.029^a	1.04 (1.00–1.08)	.052

Negative binomial regression models were estimated using 2-way fixed effects, with standard errors clustered at the country level to account for repeated observations. Multivariable models adjusted for UNAIDS region, epidemic type (generalized or mixed or concentrated), log-transformed annual number of children living with HIV, log-transformed population size, and World Bank income classification quartiles.

Values represent statistically significant incidence rate ratios (at the P < .05 level or below).