Some key aspects of iron transport in mammals (A) and insects (B) are shown. Abbreviations: Cp, ceruloplasmin; DCytb, duodenal cytochrome b; DMT1, divalent metal transporter 1; FLVCR, feline leukemia virus subgroup C receptor; HCP1, heme carrier protein 1; HO, Heme Oxygenase; Heph, hephaestin; Mvl, Malvolio, Nemy, No extended memory; STEAP, six-transmembrane epithelial antigen of the prostate; Tsf1, Tranferrin 1; Zip, Zinc-regulated, iron-regulated transporter-like protein. Not shown: PCBP, Poly(rC)-binding protein; ZnT, Zinc Transporter.