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. 2024 Jan 17;626(7997):151–159. doi: 10.1038/s41586-023-06922-8

Extended Data Fig. 7. Affinity-optimizing SNVs are significantly associated with GOF enhancer activity.

Extended Data Fig. 7

Enhancers containing SNVs that increase ETS affinity are significantly enriched in GOF expression relative to all other SNVs within a 2% sequence mutagenesis assay of the ZRS enhancer5. The bounds of the box plots define the 25th, 50th and 75th percentiles, and whiskers are 1.5 × the interquartile range. One-tailed Mann–Whitney U test.

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