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. 2023 Oct 26;20(2):221–233. doi: 10.1038/s41589-023-01452-w

Extended Data Fig. 8. Oxygen consumption rate (OCR) and OXPHOS complex expression levels in RTN4IP1-KD C2C12 and RTN4IP1-overexpressed (RTN4IP1-OE) C2C12 cells.

Extended Data Fig. 8

(a) Measurement of oxygen consumption rate (OCR), basal respiration, maximal respiration, and ATP production in control (siSCR) and Rtn4ip1 knockdown C2C12 cells (siRtn4ip1). (n = 46 biological replicates) (b) Oxygen consumption rate (OCR) and basal respiration, ATP production, and maximal respiration of RTN4IP1-overexpressed (RTN4IP1-OE) C2C12 cells. GFP-overexpressed cells were used as a control. (n = 30 biological replicates) (c) Oxygen consumption rate (OCR) and basal respiration, ATP production, and maximal respiration of RTN4IP1-rescued C2C12 cells. GFP-overexpressed cells were used as a control. (n = 30 biological replicates) Mean values are shown with error bars representing the standard deviation. Statistical significance was determined using a two-tailed Student’s t-test: *p < 0.05, **p < 0.01, ***p < 0.001. Source data can be found in the Source Data file.

Source data