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(A) Survival of C57BL/6 mice treated (triangles) or not treated (squares) with 2.5% aminoguanidine in drinking water after infection with 106 (open symbols) or 107 (closed symbols) S. flexneri 2457T organisms. (B) Survival of NOS2−/− (triangles) and control (F2 C57BL/6 × 129Sv) (squares) mice following infection with 106 (open symbols) or 107 (closed symbols) 2457T organisms. Each experimental group contained five to nine mice.
