Fig. 10.

Effect of prenatal dexamethasone treatment and acute stress in adulthood on the level of MeCP2 (A) and HDAC5 (B) in the nuclear fraction and reelin glycoprotein in tissue homogenate (C) in the frontal cortex and hippocampus (D, E, and F, respectively) of male rats; the level of proteins was assessed with Western blot (MeCP2 and HDAC5) or ELISA (reelin) and expressed as fold change or in ng/mg of protein (reelin); bar graphs represent the mean ± SEM. Statistics: two-way ANOVA, followed by the Duncan post hoc test; n = 9–10; *p < 0.05; in the case of HDAC5, DEX main effect was significant at F_1,35 = 13.786; p = 0.0007 in the frontal cortex and F_1,35 = 6.068; p = 0.019 in the hippocampus; also, regarding reelin in the frontal cortex, DEX main effect was significant at F_1,32 = 4.976; p = 0.033