Fig. 8.

Effect of prenatal dexamethasone treatment and acute stress in adulthood on the level of corticosterone in the serum (A), as well as glucocorticoid and mineralocorticoid receptors (B), and FKBP1 protein (C) in the frontal cortex and hippocampus (D and E, respectively) of male rats; the level of corticosterone and FKBP1 protein was measured using ELISA and expressed in ng/ml and ng/mg of protein, respectively, while glucocorticoid and mineralocorticoid receptors level was determined with Western blot and expressed as a fold change; bar graphs represent the mean ± SEM. Statistics: two-way ANOVA, followed by the Duncan post hoc test; n = 8–10; *p < 0.05; in the case of FKBP51 in the hippocampus, DEX main effect was significant at F_1,30 = 6.419; p = 0.017