Table 1.
Demographics of the DAISY cohort for the Control, Pre-IA, Post-IA, and Pre-T1D samples
| CTRL (N = 40) | Pre-IA (N = 47) | p value | Post-IA (N = 131) | p value | |
|---|---|---|---|---|---|
| Female; N(%) | 16(40.0) | 19(40.4) | 0.968 | 63(48.1) | 0.469 |
| HLA; N(%) | |||||
| DR3/3 or DR3/X | 6(15.0) | 5(10.6) | 12(17.6) | ||
| DR3/4 | 11(27.5) | 15(31.9) | 48(36.6) | ||
| DR4/4 or DR4/X | 22(55.0) | 21(44.7) | 44(33.6) | ||
| DRX/X | 1(2.5) | 6(12.8) | 0.309 | 16(12.2) | 0.048 |
| First-degree relative; N(%) | 9(22.5) | 27(57.5) | 0.001 | 83(63.4) | <0.001 |
| Age (machine learning) | 2.976 | 3.024 | 0.107 | ||
The Pre-IA, Post-IA, and Pre-T1D are compared to control where sex, HLA, and first-degree relative are compared to the control group via χ2 test of independence and age is compared via a two-sample test.