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Apical-to-basolateral diffusion (expressed as percent permeability; % permeability) for Transwells with confluent PTEC monolayers at time = 0 h and following culture under normoxic (control) or hypoxic conditions (time = 72 h). Results represent mean ± SEM of eight individual PTEC donor experiments.
| Condition | % Permeability (n = 8) |
|---|---|
| Time = 0 h | |
| Confluent monolayer | 0.55 ± 0.14 |
| Time = 72 h | |
| Normoxia | 0.75 ± 0.05 |
| Hypoxia | 0.70 ± 0.13 |
