Table 4.
Daytime and nighttime urinary excretion and concentrations by quartiles of day-to-night ratio of urinary sodium and potassium excretion rate
|
Variable |
Day-to-night ratio of the urinary sodium excretion |
Day-to-night ratio of the urinary potassium excretion |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Q1 ≤ 1.00 (n = 788) |
Q2 1.01-1.52 (n = 788) |
Q3 1.53-2.52 (n = 788) |
Q4 > 2.52 (n = 788) |
P Value | Q1 ≤ 1.44 (n = 788) |
Q2 1.44-1.94 (n = 788) |
Q3 1.95-2.62 (n = 787) |
Q4 > 2.62 (n = 789) |
P Value | |
| Day | ||||||||||
| Day Va (L) | 0.84 (0.59–1.13) | 1.11 (0.80–1.48) | 1.19 (0.89–1.61) | 1.39 (0.95–1.85) | < 0.001 | 0.80 (0.55–1.13) | 1.08 (0.8–1.48) | 1.23 (0.91–1.60) | 1.34 (0.99–1.83) | < 0.001 |
| Day V† (ml/h) | 0.93 (0.66–1.26) | 1.23 (0.89–1.64) | 1.32 (0.99–1.79) | 1.54 (1.06–2.06) | < 0.001 | 0.89 (0.61–1.26) | 1.20 (0.89–1.64) | 1.37 (1.01–1.78) | 1.49 (1.10–2.03) | < 0.001 |
| Day Na excretion (mmol) | 46.52 (29.04–67.26) | 69.00 (48.35–96.37) | 83.97 (58.36–116.48) | 94.66 (61.93–133.78) | < 0.001 | 50.61 (32.00–77.33) | 67.18 (45.60–97.58) | 79.52 (54.29–113.90) | 90.92 (60.87–129.60) | < 0.001 |
| Day UNa (mmol/l) | 59.00 (38.00–83.28) | 64.37 (44.42–90.00) | 69.78 (48.87–96.66) | 71.00 (50.00–99.65) | < 0.001 | 66.08 (42.49–93.64) | 63.61 (43.70–89.87) | 66.00 (46.00–90.10) | 68.90 (48.00–97.34) | 0.032 |
| Day K excretion (mmol) | 17.26 (11.77–23.33) | 20.48 (15.72–26.76) | 22.53 (16.90–28.96) | 23.46 (17.32–31.48) | < 0.001 | 15.29 (10.73–20.12) | 19.94 (15.65–25.80) | 22.95 (18.08–28.52) | 26.62 (20.23–35.35) | < 0.001 |
| Day UK (mmol/l) | 21.74 (14.12–30.78) | 19.15 (13.90–25.71) | 18.87 (13.61–26.10) | 18.12 (12.70–25.26) | < 0.001 | 19.15 (12.70–27.50) | 18.60 (13.40–26.30) | 19.00 (13.90–26.10) | 20.30 (14.30–28.20) | 0.015 |
| Night | ||||||||||
| Night Va(l) | 0.86 (0.63–1.15) | 0.71 (0.55–0.93) | 0.56 (0.40–0.78) | 0.36 (0.23–0.53) | < 0.001 | 0.76 (0.53–1.05) | 0.70 (0.50–0.93) | 0.61 (0.43–0.82) | 0.44 (0.26–0.65) | < 0.001 |
| Night Vb (ml/h) | 1.59 (1.17–2.13) | 1.31 (1.02–1.72) | 1.04 (0.75–1.44) | 0.67 (0.43–0.98) | < 0.001 | 1.41 (0.98–1.94) | 1.30 (0.93–1.72) | 1.13 (0.80–1.52) | 0.81 (0.48–1.20) | < 0.001 |
| Night Na excretion (mmol) | 71.61 (47.89–100.79) | 55.75 (29.23–28.56) | 44.08 (30.25–60.98) | 22.78 (13.21–35.91) | < 0.001 | 60.90 (35.41–90.18) | 52.52 (32.49–75.80) | 45.82 (27.15–65.17) | 32.24 (17.03–51.68) | < 0.001 |
| Night UNa (mmol/l) | 85.00 (61.00–109.00) | 80.19 (58.64–104.04) | 78.00 (54.00–106.49) | 66.14 (41.00–96.00) | < 0.001 | 82.00 (55.00–107.00) | 78.16 (56.00–101.00) | 76.00 (51.50–103.00) | 73.60 (50.00–107.89) | 0.164 |
| Night K excretion (mmol) | 13.34 (9.82–17.97) | 11.36 (8.73–15.11) | 10.28 (7.85–13.06) | 8.24 (5.61–11.22) | < 0.001 | 14.17 (10.26–19.10) | 11.74 (9.21–15.52) | 10.32 (8.14–12.70) | 7.52 (5.14–9.95) | < 0.001 |
| Night UK (mmol/l) | 15.80 (11.50–21.40) | 16.10 (11.75–21.92) | 17.64 (13.00–25.38) | 22.52 (14.70–33.71) | < 0.001 | 18.72 (13.34–27.04) | 17.70 (12.41–24.95) | 16.52 (12.30–24.00) | 17.11 (12.20–25.52) | 0.001 |
| D/N | ||||||||||
| D/N Va | 0.95 (0.70–1.24) | 1.46 (1.2–1.81) | 2.07 (1.66–2.67) | 3.60 (2.55–5.35) | < 0.001 | 1.03 (0.73–1.47) | 1.55 (1.17–2.04) | 1.95 (1.48–2.73) | 3.08 (2.17–4.71) | < 0.001 |
| D/N Na Va | 0.73 (0.56–0.87) | 1.24 (1.11–1.38) | 1.91 (1.72–2.16) | 3.63 (2.93–5.33) | < 0.001 | 0.88 (0.60–1.24) | 1.29 (0.98–1.79) | 1.74 (1.30–2.50) | 2.87 (1.96–4.37) | < 0.001 |
| D/N K Va | 1.28 (0.98–1.65) | 1.77 (1.47–2.19) | 2.19 (1.77–2.78) | 2.85 (2.23–4.10) | < 0.001 | 1.14 (0.90–1.29) | 1.69 (1.56–1.81) | 2.24 (2.09–2.40) | 3.39 (2.90–4.42) | < 0.001 |
| D/N Vb | 0.57 (0.42–0.75) | 0.88 (0.72–1.08) | 1.24 (1.00–1.60) | 2.16 (1.53–3.21) | < 0.001 | 0.62 (0.44–0.88) | 0.92 (0.70–1.23) | 1.17 (0.89–1.64) | 1.85 (1.30–2.82) | < 0.001 |
| D/N Na Vb | 0.44 (0.33–0.52) | 0.75 (0.67–0.83) | 1.15 (1.03–1.30) | 2.18 (1.76–3.20) | < 0.001 | 0.53 (0.36–0.74) | 0.77 (0.59–1.07) | 1.05 (0.78–1.50) | 1.72 (1.17–2.62) | < 0.001 |
| D/N K Vb | 0.77 (0.59–0.99) | 1.06 (0.88–1.31) | 1.31 (1.06–1.67) | 1.71 (1.34–2.46) | < 0.001 | 0.68 (0.54–0.78) | 1.02 (0.94–1.08) | 1.34 (1.26–1.44) | 2.03 (1.74–2.65) | < 0.001 |
D/N, daytime/nighttime.
a
urine volumes represent in l.
b
urine flow rates in mL/h. Na, sodium; K, potassium; UNa, urinary sodium; UK, urinary potassium.