Table 3.

Exercise timing and exerkine/myokine level.

Exerkine/myokine	Level of exerkine after morning exercise	Level of exerkine after evening exercise
Nrf2 signaling	Low	High
IL-6	Low	High
AICAR	Low	High
AMPK	Low	High
CRY1/2	High	Low
PPAR-δ	Low	High
PGAM5	High	Low

Abbreviation: Nrf2= Nuclear factor E2 related factor-2, IL-6 ​= ​interleukin-6, AICAR ​= ​5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside, AMPK ​= ​AMP-activated protein kinase, CRY1/2 ​= ​Cryptochrome 1/2 ​= ​PPAR-δ ​= ​Peroxisome proliferator-activated receptors-δ, PGAM5 ​= ​mitochondrial serine/threonine-protein phosphatase.