Table 3.
Subgroup analysis of clinical PR according to age, DAF, embryo quality and quantity, ovarian stimulation protocol, and endometrial thickness in cleavage embryos/blastocysts FET cycles.
Variables | Day 3 embryos | Day 5 embryos | ||||
---|---|---|---|---|---|---|
n/total n | % | P | n/total n | % | P | |
Age, years | 0.002 | 0.000 | ||||
≤30 | 58/104 | 55.7 | 309/420 | 73.6 | ||
31–37 | 101/184 | 54.8 | 223/369 | 60.4 | ||
>37 | 6/29 | 20.6 | 31/53 | 58.5 | ||
DAF, mm | 0.039 | 0.043 | ||||
≤3 | 7/21 | 33.3 | 34/54 | 63.0 | ||
3–15 | 153/280 | 55.0 | 485/708 | 68.5 | ||
≥15 | 5/16 | 31.3 | 44/80 | 55.0 | ||
Embryo quality and quantity | 0.000 | − | ||||
SET day 3 (A/B) | 16/49 | 32.7 | ||||
DET day 3 (B + B) | 25/64 | 39.0 | ||||
DET day 3 (A + B) | 53/99 | 53.5 | ||||
DET day 3 (A + A) | 71/105 | 67.6 | ||||
SET day 5 (B) | − | − | 42/87 | 48.2 | 0.000 | |
SET day 5 (A) | 437/647 | 67.5 | ||||
DET day 5 (A/B+ A/B) | − | − | 84/108 | 77.8 | ||
Ovarian stimulation protocol | 0.152 | 0.342 | ||||
GnRH antagonist protocol | 78/154 | 50.6 | 318/463 | 68.6 | ||
Luteal phase short-acting long protocol | 59/104 | 56.7 | 173/276 | 62.6 | ||
Follicular phase long-acting long protocol | 18/30 | 60.0 | 64/92 | 69.5 | ||
Others | 10/29 | 34.5 | 8/11 | 72.7 | ||
Endometrial thickness, mm | 0.010 | 0.021 | ||||
<4 | 3/15 | 20 | 26/50 | 52.0 | ||
≥4 | 162/302 | 53.6 | 537/792 | 67.8 |
‘A’ presents high-quality embryo; ‘B’ presents non-high-quality embryo.
DAF, distance from the air bubble to endometrial cavity fundus; DET, double embryos transfer; PR, pregnancy rate; SET, single embryo transfer.