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. 2024 Jan 17;11:e47031. doi: 10.2196/47031

Table 2.

Other factors related to trust (N=110) in medical AIa applications (22/32, 68.8%, studies).

Factor category and factors from the rapid review Umbrella factors used in the survey
Technology-related factors

Accuracy (n=7, 31.8%); reliability (n=5, 22.7%); safety (n=4, 18.2%); design and output quality (n=2, 9.1%); performance expectancy (n=2, 9.1%); ability (n=1, 4.5%); perceived functionality (n=1, 4.5%); self-efficacy (n=1, 4.5%); tool itself (n=1, 4.5%) Performance of AI applications in medicine (reproducibility of outcomes, accuracy)

Auditability (n=1, 4.5%); customizability (n=1, 4.5%); understandability (n=1, 4.5%); ease of integration into clinical workflows (n=1, 4.5%); convenience of use (n=1, 4.5%); usability (n=1, 4.5%); (over)alerting and excessive false-positive rate (n=1, 4.5%) Possibility of integration of AI applications into existing clinical workflows

Risk and impact mitigation (n=1, 4.5%) Clear balance of risks and benefits of the AI application

Transparency (n=6, 27.3%); explainability (n=5, 22.7%); evidence strength (n=2, 9.1%); benevolence (n=2, 9.1%); complexity (n=2, 9.1%); interpretability (n=2, 9.1%); integrity (n=1, 4.5%); predictability (n=1, 4.5%); trialability (n=1, 4.5%); trustworthiness (n=1, 4.5%) Explainability and transparency of the processes and outcomes
Legal and ethical factors

Fairness and equity (n=8, 36.4%); adequate regulations, legislation, and governance (n=3, 13.6%); ethical/legal implications (n=1, 4.5%) Adequacy of the regulations and governance of AI applications in medicine

Personal data privacy and security (n=8, 36.4%); data used to train AI/cognitive bias (n=2, 9.1%); data sensitivity (n=1, 4.5%); respect and preservation of human dignity (n=1, 4.5%) Data use transparency

Accountability (n=3, 13.6%); power-control balance (n=1, 4.5%) Clear accountability and responsibility of the AI application (machine vs human responsibility)
Additional factors

Environmental sustainability (n=1, 4.5%) Environment-friendly AI application

Replacement of doctor/lack of human touch and moral support when evaluated by AI alone (n=1, 4.5%); labor market implications (n=1, 4.5%) Impact on job availability (machines replacing humans)

aAI: artificial intelligence.