TABLE 2.
Immunity of mice to tetanus and salmonellaea
| Immunogen | No. survivors/5 challenged
|
|
|---|---|---|
| Tetanus challenge | Salmonella challenge | |
| BRD847 | 5 | 5 |
| BRD937 | 5 | 5 |
| Frg C + alhydrogel | 5 | 0 |
| BRD509 | 0 | ND |
| None | 0 | 0 |
a
Fifteen weeks after immunization, mice were challenged s.c. with 50 LD50 of tetanus toxin. Animals were monitored for signs of tetanus for 4 days. Two weeks after tetanus challenge, surviving and naive control mice were orally challenged with 8 × 108 CFU of wild-type S. typhimurium SL1344. Mice were observed for 28 days, and fatalities were recorded. ND, not determined.