Table 3.
Maternal and neonatal outcomes | References | Studies, n (%) | Sample size | Statistical method | Effect estimates (95% CI) | P value | |||||||
Maternal outcomes | |||||||||||||
|
Postpartum hemorrhage (%) | 6 (38) | 4664 | Odds ratio (IVa; fixed) | 1.06 (0.90 to 1.24) | .49 | |||||||
|
Cesarean delivery (%) | 9 (56) | 5224 | Odds ratio (IV; fixed) | 0.89 (0.79 to 1.00) | .05 | |||||||
|
Preeclampsia or PIHb (%) | 9 (56) | 5829 | Odds ratio (IV; fixed) | 0.96 (0.80 to 1.15) | .63 | |||||||
|
GWGc (kg) | 8 (50) | 4133 | Mean difference (IV; fixed) | −1.12 (−1.44 to −0.80) | <.001 | |||||||
Neonatal outcomes | |||||||||||||
|
Preterm birth (%) | 7 (44) | 2998 | Odds ratio (IV; fixed) | 0.65 (0.48 to 0.87) | .004 | |||||||
|
Macrosomia (%) | 9 (56) | 4449 | Odds ratio (IV; random) | 0.59 (0.40 to 0.87) | .008 | |||||||
|
LGAd >90th percentile (%) | 5 (31) | 4966 | Odds ratio (IV; random) | 0.80 (0.60 to 1.06) | .12 | |||||||
|
SGAe <10th percentile (%) | 4 (25) | 1529 | Odds ratio (IV; fixed) | 1.10 (0.78 to 1.55) | .60 |
aIV: inverse variance.
bPIH: pregnancy-induced hypertension.
cGWG: gestational weight gain.
dLGA: large for gestational age.
eSGA: small for gestational age.