TABLE 1.

Vacuolating cytotoxin activities and vacA transcriptional activities of H. pylori strains used in this study

Strain	vacA genotype	cagA	Vacuolating activity for HeLa cellse	vacA primer extension sig- nal intensityf
60190 (ATCC 49503)	s1a/m1a	+	160	25.0
84-183 (ATCC 53726)	s1b/m1b	+	80	11.9
87-33	s1b/m1	+	20	12.9
87-81	s1b/m1b	+	320	20.1
92-25	s1b/m1	+	20	16.3
92-29	s1b/m1	+	80	15.8
92-26	s1b/m1	+	20	6.8
87-199	s1a/m1	+	320	17.4
86-338	s2/m2	−	<10	19.1
Tx30a (ATCC 51932)	s2/m2c	−	<10	8.3
86-313	s2/m2b	−	<10	8.9
87-75	s2/m2	−	<10	4.8
87-203	s2/m2d	−	<10	8.9
92-28	s2/m2	−	<10	8.6
87-90	s2/m2	−	<10	3.3
87-230	s2/m2	−	<10	9.6
92-20	s2/m2	−	<10	0

^aGenBank accession no. U05676 (10). 

^bPartial vacA sequence from this strain has been reported previously (2). 

^cGenBank accession no. U29401 (2). 

^dGenBank accession no. U05677 (10). 

^eReciprocal titer of the maximum supernatant dilution that produced vacuolation of HeLa cells. 

^fQuantified by laser densitometry (OD per square millimeter).