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. 2024 Jan 17;10(2):e24840. doi: 10.1016/j.heliyon.2024.e24840

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© 2024 Published by Elsevier Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Effects of thymoquinone on Bcl-2, Bax, and caspase-3 expression in rat kidney in cisplatin induced nephrotoxicity in rats (n = 3). a: Western blot of Bcl-2, Bax and caspase-3 expression in rat kidney in cisplatin induced nephrotoxicity in rats b: Statistical analysis plot of the effect of thymoquinone on Bcl-2, Bax and caspase-3 expression in rat kidney in cisplatin induced nephrotoxicity in rats *: Significantly different from group B; #: Significantly different from group A

Group A: normal control group, Group B: in rats treated with cisplatin only, Group C: in rats treated with cisplatin and 1 mg/kg thymoquinone, Group D: in rats treated with cisplatin and 3 mg/kg thymoquinone, Group E: in rats treated with cisplatin and 5 mg/kg thymoquinone, Group F: in rats treated with cisplatin and 10 mg/kg thymoquinone, Group G: in rats treated with cisplatin and 20 mg/kg thymoquinone.