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IFN-γ production for PBMC stimulated with individual P-4 peptides. PBMC from patients 10 through 22 were stimulated with individual P-4 peptides for 5 days. Supernatants were harvested and IFN-γ levels were measured by ELISA, as indicated in Materials and Methods. The total IFN-γ produced is presented for cases where significant levels (≥20 pg/ml) were observed in response to the indicated individual peptide.
