TABLE 2.
Peptide group | SI for patient:
|
Total no. of responsive patients | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | ||
I | —b | 6.8 | — | 2.8 | — | — | — | 2.6 | — | — | — | — | 2.6 | 3.4 | — | — | 5 |
II | — | 9.2 | 5.2 | 2.6 | — | — | — | 2.6 | — | — | — | — | — | — | — | — | 4 |
III | — | 7.7 | — | — | — | — | — | 3.0 | — | — | — | — | — | 5.0 | — | — | 3 |
IV | — | 8.1 | — | — | — | — | 2.5 | — | — | — | — | — | 3.1 | 3.0 | — | — | 4 |
V | — | 4.5 | — | 2.6 | — | — | 3.5 | — | — | — | — | — | — | 2.9 | — | — | 4 |
VI | — | 6.5 | — | — | — | — | 3.1 | — | — | — | — | — | — | 4.3 | — | — | 3 |
VII | — | — | — | — | — | — | 2.5 | — | — | — | — | — | — | 7.6 | — | — | 2 |
VIII | — | 4.2 | — | — | — | — | 2.8 | 2.9 | — | — | 2.5 | — | — | 5.5 | — | — | 5 |
PBMC from patients 1 through 16 were stimulated with groups of peptides as described in Material and Methods. After 5 days of antigenic stimulation, [3H]thymidine incorporation was measured as a marker of cell proliferation.
—, SI of <2.5.