Table 4:
Hemodynamics and PBF at 20-weeks for all groups
| Sham (n=4) | LPAS (n=4) | Delayed Intervention (n=5) | Early Intervention (n=5) | |
|---|---|---|---|---|
| BW (kg) | 56±3 | 57±2 | 59±3 | 48±5 |
| HR (BPM) | 84±4 | 83±2 | 105±6 | 96±8 |
| Fulton Index (g/g) | 0.42±0.02 | 0.40±0.02 | 0.44±0.02 | 0.40±0.02 |
| CI (L/min/m2) | 2.8±0.2 | 3.2±0.1 | 3.7±0.4 | 3.6±0.3 |
| L Lung Perfusion (%) | 52±5 | 7±2* | 44±3 (n=4) | 40±2 |
| Mean RA Pressure (mmHg) | 7±2 | 10±1 | 6±1 | 6±1# (n=4) |
| RV Systolic Pressure (mmHg) | 28±3 / 7±2 | 38±3 / 10±1 | 27±2# / 7±1 | 29±1 / 6±0 (n=4) |
| MPA Pressure (sys / dia, mmHg) | 29±2 / 14±2 | 38±3 / 17±2 | 25±1# / 13±0 | 28±1 / 13±2 (n=4) |
| RPA Pressure (sys / dia, mmHg) | 27±2 / 15±2 | 37±2 / 18±2 | 25±2 / 14±1 | 24±2# / 13±1 (n=4) |
| LPA Pressure (sys / dia, mmHg) | 28±1 / 17±1 | 15±4* / 13±4 | 23±2 / 14±1 | 22±2 / 13±2 (n=4) |
| Stenosis/Stent Pressure Gradient (mmHg) | 1±2 | 23±3* | 1±1# | 6±1 (n=4) |
| PCWP (mmHg) | 10±1 | 11±3 | 8±1 | 7±1 (n=4) |
*
p<0.05 vs sham control,
#
p<0.05 vs LPAS control