Figure 29.
SAR of 5-benzalhydantoin using CoMFA toward c-Met. Adapted with permission from Mudit, M.; Khanfar, M.; Muralidharan, A.; Thomas, S.; Shah, G. V.; van Soest, R. W. M.; Sayed, K. A. E. Discovery, Design, and Synthesis of Anti-Metastatic Lead Phenylmethylene Hydantoins Inspired by Marine Natural Products. Bioorganic & Medicinal Chemistry2009, 17 (4), 1731–1738. 10.1016/j.bmc.2008.12.053.75 Copyright 2009. Elsevier.